1. Immediate myeloid depot for SARS-CoV-2 in the human lung. Sci Adv. 2024 Aug 02; 10(31):eadm8836.Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Bernard O, Simoneau CR, Hysenaj L, Hu KH, Maishan M, Conrad C, Gbenedio OM, Samad B, Consortium TUC, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. PMID: 39083602; PMCID: PMC11290487.
2. Long-term air pollution exposure and the risk of primary graft dysfunction after lung transplantation. J Heart Lung Transplant. 2024 Jul 15.Koyama T, Zhao Z, Balmes JR, Calfee CS, Matthay MA, Reilly JP, Porteous MK, Diamond JM, Christie JD, Cantu E, Ware LB, Lung Transplant Outcomes Group. PMID: 39019353.
3. From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. Am J Respir Crit Care Med. 2024 07 15; 210(2):155-166.Gordon AC, Alipanah-Lechner N, Bos LD, Dianti J, Diaz JV, Finfer S, Fujii T, Giamarellos-Bourboulis EJ, Goligher EC, Gong MN, Karakike E, Liu VX, Lumlertgul N, Marshall JC, Menon DK, Meyer NJ, Munroe ES, Myatra SN, Ostermann M, Prescott HC, Randolph AG, Schenck EJ, Seymour CW, Shankar-Hari M, Singer M, Smit MR, Tanaka A, Taccone FS, Thompson BT, Torres LK, van der Poll T, Vincent JL, Calfee CS. PMID: 38687499; PMCID: PMC11273306.
4. Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Nat Commun. 2024 Jun 28; 15(1):5483.Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. PMID: 38942804; PMCID: PMC11213873.
5. Biological effects of corticosteroids on pneumococcal pneumonia in Mice-translational significance. Crit Care. 2024 05 29; 28(1):185.Taenaka H, Wick KD, Sarma A, Matsumoto S, Ghale R, Fang X, Maishan M, Gotts JE, Langelier CR, Calfee CS, Matthay MA. PMID: 38807178; PMCID: PMC11134653.
6. Neutrophil Reduction Attenuates the Severity of Lung Injury in the Early Phase of Pneumococcal Pneumonia in Mice. Am J Physiol Lung Cell Mol Physiol. 2024 May 21.Taenaka H, Fang X, Maishan M, Trivedi A, Wick KD, Gotts JE, Martin TR, Calfee CS, Matthay MA. PMID: 38772909.
7. Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis. Crit Care. 2024 05 14; 28(1):164.Evrard B, Sinha P, Delucchi K, Hendrickson CM, Kangelaris KN, Liu KD, Willmore A, Wu N, Neyton L, Schmiege E, Gomez A, Kerchberger VE, Zalucky A, Matthay MA, Ware LB, Calfee CS. PMID: 38745253; PMCID: PMC11092165.
8. Acute respiratory distress syndrome guidelines: oceans apart or rivers that merge? Intensive Care Med. 2024 Jun; 50(6):941-943.Camporota L, Calfee CS, Grasselli G. PMID: 38709291.
9. Smoking-Attributable Health Care Expenditures for US Adults With Chronic Lower Respiratory Disease. JAMA Netw Open. 2024 May 01; 7(5):e2413869.Gu D, Sung HY, Calfee CS, Wang Y, Yao T, Max W. PMID: 38814643; PMCID: PMC11140527.
10. Rapidly improving ARDS differs clinically and biologically from persistent ARDS. Crit Care. 2024 04 22; 28(1):132.Valda Toro PL, Willmore A, Wu NE, Delucchi KL, Jauregui A, Sinha P, Liu KD, Hendrickson CM, Sarma A, Neyton LPA, Leligdowicz A, Langelier CR, Zhuo H, Jones C, Kangelaris KN, Gomez AD, Matthay MA, Calfee CS. PMID: 38649920; PMCID: PMC11034037.
11. Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Sci Transl Med. 2024 Apr 17; 16(743):eadj5154.Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. PMID: 38630846.
12. The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia. Am J Respir Crit Care Med. 2024 04 15; 209(8):973-986.Chouchane O, Schuurman AR, Reijnders TDY, Peters-Sengers H, Butler JM, Uhel F, Schultz MJ, Bonten MJ, Cremer OL, Calfee CS, Matthay MA, Langley RJ, Alipanah-Lechner N, Kingsmore SF, Rogers A, van Weeghel M, Vaz FM, van der Poll T. PMID: 38240721.
13. Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes. Am J Respir Crit Care Med. 2024 Apr 01; 209(7):805-815.Neyton LPA, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, Wu N, Delucchi K, Zhuo H, Bos LDJ, Jauregui A, Gomez A, Hendrickson CM, Kangelaris KN, Leligdowicz A, Liu KD, Matthay MA, Langelier CR, Calfee CS. PMID: 38190719; PMCID: PMC10995577.
14. Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time. Am J Respir Crit Care Med. 2024 Apr 01; 209(7):816-828.Sinha P, Neyton L, Sarma A, Wu N, Jones C, Zhuo H, Liu KD, Sanchez Guerrero E, Ghale R, Love C, Mick E, Delucchi KL, Langelier CR, Thompson BT, Matthay MA, Calfee CS. PMID: 38345571; PMCID: PMC10995566.
15. Critical Care: A Second Special Issue of the Blue Journal. Am J Respir Crit Care Med. 2024 04 01; 209(7):769-771.Calfee CS, Harhay MO, Schenck EJ, Ferguson ND, Heunks L, White D, Brochard LJ. PMID: 38501798; PMCID: PMC10995575.
16. Smoking primes the metabolomic response in trauma. J Trauma Acute Care Surg. 2024 Jul 01; 97(1):48-56.Gallagher LT, Erickson C, D'Alessandro A, Schaid T, Thielen O, Hallas W, Mitra S, Stafford P, Moore EE, Silliman CC, Calfee CS, Cohen MJ. PMID: 38548690; PMCID: PMC11199115.
17. Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort. Crit Care. 2024 03 21; 28(1):91.Ceccato A, Forne C, Bos LD, Camprubí-Rimblas M, Areny-Balagueró A, Campaña-Duel E, Quero S, Diaz E, Roca O, De Gonzalo-Calvo D, Fernández-Barat L, Motos A, Ferrer R, Riera J, Lorente JA, Peñuelas O, Menendez R, Amaya-Villar R, Añón JM, Balan-Mariño A, Barberà C, Barberán J, Blandino-Ortiz A, Boado MV, Bustamante-Munguira E, Caballero J, Carbajales C, Carbonell N, Catalán-González M, Franco N, Galbán C, Gumucio-Sanguino VD, de la Torre MDC, Estella Á, Gallego E, García-Garmendia JL, Garnacho-Montero J, Gómez JM, Huerta A, Jorge-García RN, Loza-Vázquez A, Marin-Corral J, Martínez de la Gándara A, Martin-Delgado MC, Martínez-Varela I, Messa JL, Muñiz-Albaiceta G, Nieto MT, Novo MA, Peñasco Y, Pozo-Laderas JC, Pérez-García F, Ricart P, Roche-Campo F, Rodríguez A, Sagredo V, Sánchez-Miralles A, Sancho-Chinesta S, Socias L, Solé-Violan J, Suarez-Sipmann F, Tamayo-Lomas L, Trenado J, Úbeda A, Valdivia LJ, Vidal P, Bermejo J, Gonzalez J, Barbe F, Calfee CS, Artigas A, Torres A, CIBERESUCICOVID Project. PMID: 38515193; PMCID: PMC10958830.
18. Identification of a hyperinflammatory sepsis phenotype using protein biomarker and clinical data in the ProCESS randomized trial. Sci Rep. 2024 03 14; 14(1):6234.DeMerle KM, Kennedy JN, Chang CH, Delucchi K, Huang DT, Kravitz MS, Shapiro NI, Yealy DM, Angus DC, Calfee CS, Seymour CW. PMID: 38485953; PMCID: PMC10940677.
19. Critical Care: A Special Issue of the Blue Journal. Am J Respir Crit Care Med. 2024 03 01; 209(5):465-467.Calfee CS, Harhay MO, Schenck EJ, Ferguson ND, Heunks L, White DB, Brochard LJ. PMID: 38300147; PMCID: PMC10919106.
20. The Translational Value of Rodent Models of Sepsis. Am J Respir Crit Care Med. 2024 Mar 01; 209(5):488-490.Matthay MA, Schmidt EP, Bastarache JA, Calfee CS, Frevert CW, Martin TR. PMID: 38091521; PMCID: PMC10919117.
21. Biological Effects of Corticosteroids on Pneumococcal Pneumonia in Mice and Humans. Res Sq. 2024 Feb 21.Taenaka H, Wick KD, Sarma A, Matsumoto S, Ghale R, Fang X, Maishan M, Gotts JE, Langelier CR, Calfee CS, Matthay MA. PMID: 38464245; PMCID: PMC10925444.
22. Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial. Crit Care. 2024 02 21; 28(1):56.Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS, I-SPY COVID Consortium. PMID: 38383504; PMCID: PMC10882728.
23. Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax. 2024 Feb 15; 79(3):227-235.Mehta P, Samanta RJ, Wick K, Coll RC, Mawhinney T, McAleavey PG, Boyle AJ, Conlon J, Shankar-Hari M, Rogers A, Calfee CS, Matthay MA, Summers C, Chambers RC, McAuley DF, O'Kane CM. PMID: 38148147.
24. Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology. medRxiv. 2024 Feb 13.Van Phan H, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, Van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns C, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. PMID: 38405760; PMCID: PMC10888993.
25. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nat Commun. 2024 Jan 03; 15(1):216.Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LIR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Higuita NIA, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE, IMPACC Network, Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Maecker HT, Altman MC, Montgomery RR, Becker PM, Rouphael N. PMID: 38172101; PMCID: PMC10764789.
26. The antibiotic resistance reservoir of the lung microbiome expands with age in a population of critically ill patients. Nat Commun. 2024 Jan 02; 15(1):92.Chu VT, Tsitsiklis A, Mick E, Ambroggio L, Kalantar KL, Glascock A, Osborne CM, Wagner BD, Matthay MA, DeRisi JL, Calfee CS, Mourani PM, Langelier CR. PMID: 38168095; PMCID: PMC10762195.
27. From Berlin to Global: The Need for Syndromic Definitions of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2024 Jan 01; 209(1):21-23.Alipanah-Lechner N, Cavalcanti AB, Diaz J, Ferguson ND, Myatra SN, Calfee CS. PMID: 37816094; PMCID: PMC10870889.
28. A New Global Definition of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2024 01 01; 209(1):37-47.Matthay MA, Arabi Y, Arroliga AC, Bernard G, Bersten AD, Brochard LJ, Calfee CS, Combes A, Daniel BM, Ferguson ND, Gong MN, Gotts JE, Herridge MS, Laffey JG, Liu KD, Machado FR, Martin TR, McAuley DF, Mercat A, Moss M, Mularski RA, Pesenti A, Qiu H, Ramakrishnan N, Ranieri VM, Riviello ED, Rubin E, Slutsky AS, Thompson BT, Twagirumugabe T, Ware LB, Wick KD. PMID: 37487152; PMCID: PMC10870872.
29. The Impact of Donor Smoking on Primary Graft Dysfunction and Mortality after Lung Transplantation. Am J Respir Crit Care Med. 2024 01 01; 209(1):91-100.Diamond JM, Cantu E, Calfee CS, Anderson MR, Clausen ES, Shashaty MGS, Courtwright AM, Kalman L, Oyster M, Crespo MM, Bermudez CA, Benvenuto L, Palmer SM, Snyder LD, Hartwig MG, Todd JL, Wille K, Hage C, McDyer JF, Merlo CA, Shah PD, Orens JB, Dhillon GS, Weinacker AB, Lama VN, Patel MG, Singer JP, Hsu J, Localio AR, Christie JD. PMID: 37734031; PMCID: PMC10870879.
30. Functional recovery in a cohort of ECMO and non-ECMO acute respiratory distress syndrome survivors. Crit Care. 2023 11 14; 27(1):440.Snyder M, Njie BY, Grabenstein I, Viola S, Abbas H, Bhatti W, Lee R, Traficante R, Yeung SYA, Chow JH, Tabatabai A, Taylor BS, Dahi S, Scalea T, Rabin J, Grazioli A, Calfee CS, Britton N, Levine AR. PMID: 37964311; PMCID: PMC10644522.
31. Robust airway microbiome signatures in acute respiratory failure and hospital-acquired pneumonia. Nat Med. 2023 Nov; 29(11):2793-2804.Montassier E, Kitsios GD, Radder JE, Le Bastard Q, Kelly BJ, Panzer A, Lynch SV, Calfee CS, Dickson RP, Roquilly A. PMID: 37957375.
32. Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208]. EBioMedicine. 2023 Dec; 98:104860.Ozonoff A, Schaenman J, Jayavelu ND, Milliren CE, Calfee CS, Cairns CB, Kraft M, Baden LR, Shaw AC, Krammer F, van Bakel H, Esserman DA, Liu S, Sesma AF, Simon V, Hafler DA, Montgomery RR, Kleinstein SH, Levy O, Bime C, Haddad EK, Erle DJ, Pulendran B, Nadeau KC, Davis MM, Hough CL, Messer WB, Agudelo Higuita NI, Metcalf JP, Atkinson MA, Brakenridge SC, Corry D, Kheradmand F, Ehrlich LIR, Melamed E, McComsey GA, Sekaly R, Diray-Arce J, Peters B, Augustine AD, Reed EF, Altman MC, Becker PM, Rouphael N, IMPACC Study Group Members. PMID: 37918220; PMCID: PMC10643088.
33. Simvastatin in Critically Ill Patients with Covid-19. N Engl J Med. 2023 12 21; 389(25):2341-2354.REMAP-CAP Investigators, Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. PMID: 37888913; PMCID: PMC10755839.
34. Acute respiratory distress syndrome phenotypes with distinct clinical outcomes in PHARLAP trial cohort. Crit Care Resusc. 2021 Jun; 23(2):163-170.Bihari S, Bersten A, Paul E, McGuinness S, Dixon D, Sinha P, Calfee CS, Nichol A, Hodgson C, PHARLAP Study Investigators. PMID: 38045528; PMCID: PMC10692525.
35. The antibiotic resistance reservoir of the lung microbiome expands with age. Res Sq. 2023 Sep 18.Chu VT, Tsitsiklis A, Mick E, Ambroggio L, Kalantar KL, Glascock A, Osborne CM, Wagner BD, Matthay MA, DeRisi JL, Calfee CS, Mourani PM, Langelier CR. PMID: 37790384; PMCID: PMC10543260.
36. Elevated Plasma Interleukin-18 Identifies High-Risk Acute Respiratory Distress Syndrome Patients not Distinguished by Prior Latent Class Analyses Using Traditional Inflammatory Cytokines: A Retrospective Analysis of Two Randomized Clinical Trials. Crit Care Med. 2023 12 01; 51(12):e269-e274.Moore AR, Pienkos SM, Sinha P, Guan J, O'Kane CM, Levitt JE, Wilson JG, Shankar-Hari M, Matthay MA, Calfee CS, Baron RM, McAuley DF, Rogers AJ. PMID: 37695136; PMCID: PMC10840968.
37. Subphenotypes of Acute Respiratory Distress Syndrome: Advancing Towards Precision Medicine. Tuberc Respir Dis (Seoul). 2024 Jan; 87(1):1-11.Levine AR, Calfee CS. PMID: 37675452; PMCID: PMC10758309.
38. A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling. iScience. 2023 Oct 20; 26(10):107813.Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ, UCSF COMET Consortium, Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM. PMID: 37810211; PMCID: PMC10551843.
39. Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials. Lancet Respir Med. 2023 Nov; 11(11):965-974.Sinha P, Kerchberger VE, Willmore A, Chambers J, Zhuo H, Abbott J, Jones C, Wickersham N, Wu N, Neyton L, Langelier CR, Mick E, He J, Jauregui A, Churpek MM, Gomez AD, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Delucchi KL, Liu KD, Russell JA, Matthay MA, Walley KR, Ware LB, Calfee CS. PMID: 37633303; PMCID: PMC10841178.
40. Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Res Sq. 2023 Aug 03.Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. PMID: 37577607; PMCID: PMC10418533.
41. Subphenotypes Assigned to Pediatric Acute Respiratory Failure Patients Show Differing Outcomes. Am J Respir Crit Care Med. 2023 08 01; 208(3):331-333.Flori HR, Zhang M, Xie J, Yang G, Sapru A, Calfee CS, Delucchi KL, Sinha P, Curley MAQ, Dahmer MK. PMID: 37311208; PMCID: PMC10395717.
42. Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials. Thorax. 2023 10; 78(10):990-1003.Saha R, Pham T, Sinha P, Maddali MV, Bellani G, Fan E, Summers C, Douiri A, Rubenfeld GD, Calfee CS, Laffey JG, McAuley DF, Shankar-Hari M, LUNG-SAFE investigators. PMID: 37495364; PMCID: PMC10581447.
43. Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis. Intensive Care Med. 2023 08; 49(8):957-965.Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Jones TK, Anderson BJ, Ittner CA, Dunn T, Miano TA, Oniyide O, Balmes JR, Matthay MA, Calfee CS, Christie JD, Meyer NJ, Ware LB. PMID: 37470831; PMCID: PMC10561716.
44. Clinical and biological heterogeneity of multisystem inflammatory syndrome in adults following SARS-CoV-2 infection: a case series. Front Med (Lausanne). 2023; 10:1187420.Barth KE, Spottiswoode N, Hurabielle C, Subbaraj L, COMET Consortium, Calfee CS, Matthay MA, French S, Connolly A, Hewitt SM, Vannella KM, Barnett C, Langelier CR, Patterson S. PMID: 37484839; PMCID: PMC10357379.
45. ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies. Intensive Care Med. 2023 07; 49(7):727-759.Grasselli G, Calfee CS, Camporota L, Poole D, Amato MBP, Antonelli M, Arabi YM, Baroncelli F, Beitler JR, Bellani G, Bellingan G, Blackwood B, Bos LDJ, Brochard L, Brodie D, Burns KEA, Combes A, D'Arrigo S, De Backer D, Demoule A, Einav S, Fan E, Ferguson ND, Frat JP, Gattinoni L, Guérin C, Herridge MS, Hodgson C, Hough CL, Jaber S, Juffermans NP, Karagiannidis C, Kesecioglu J, Kwizera A, Laffey JG, Mancebo J, Matthay MA, McAuley DF, Mercat A, Meyer NJ, Moss M, Munshi L, Myatra SN, Ng Gong M, Papazian L, Patel BK, Pellegrini M, Perner A, Pesenti A, Piquilloud L, Qiu H, Ranieri MV, Riviello E, Slutsky AS, Stapleton RD, Summers C, Thompson TB, Valente Barbas CS, Villar J, Ware LB, Weiss B, Zampieri FG, Azoulay E, Cecconi M, European Society of Intensive Care Medicine Taskforce on ARDS. PMID: 37326646; PMCID: PMC10354163.
46. Early plasma angiopoietin-2 is prognostic for ARDS and mortality among critically ill patients with sepsis. Crit Care. 2023 06 13; 27(1):234.Rosenberger CM, Wick KD, Zhuo H, Wu N, Chen Y, Kapadia SB, Guimaraes A, Chang D, Choy DF, Chen H, Peck M, Sullivan KM, Ke S, Jauregui A, Leligdowicz A, Sinha P, Gomez AD, Kangelaris KN, Delucchi K, Liu KD, Calfee CS, Matthay MA, Hendrickson CM. PMID: 37312169; PMCID: PMC10261831.
47. Metagenomic Sequencing in the ICU for Precision Diagnosis of Critical Infectious Illnesses. Crit Care. 2023 03 21; 27(1):90.Neyton LPA, Langelier CR, Calfee CS. PMID: 36941644; PMCID: PMC10027598.
48. Aerosolized nicotine from e-cigarettes alters gene expression, increases lung protein permeability, and impairs viral clearance in murine influenza infection. Front Immunol. 2023; 14:1076772.Maishan M, Sarma A, Chun LF, Caldera S, Fang X, Abbott J, Christenson SA, Langelier CR, Calfee CS, Gotts JE, Matthay MA. PMID: 36999019; PMCID: PMC10043316.
49. Subphenotypes of frailty in lung transplant candidates. Am J Transplant. 2023 04; 23(4):531-539.Singer JP, Calfee CS, Delucchi K, Diamond JM, Anderson MA, Benvenuto LA, Gao Y, Wang P, Arcasoy SM, Lederer DJ, Hays SR, Kukreja J, Venado A, Kolaitis NA, Leard LE, Shah RJ, Kleinhenz ME, Golden J, Betancourt L, Oyster M, Brown M, Zaleski D, Medikonda N, Kalman L, Balar P, Patel S, Calabrese DR, Greenland JR, Christie JD. PMID: 36740192; PMCID: PMC11005295.
50. Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS. Am J Physiol Lung Cell Mol Physiol. 2023 03 01; 324(3):L297-L306.Alipanah-Lechner N, Neyton L, Mick E, Willmore A, Leligdowicz A, Contrepois K, Jauregui A, Zhuo H, Hendrickson C, Gomez A, Sinha P, Kangelaris KN, Liu KD, Matthay MA, Rogers AJ, Calfee CS. PMID: 36648136; PMCID: PMC9988532.
51. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes. JCI Insight. 2022 12 22; 7(24).Calabrese DR, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, Tian JJ, Aminian EA, Wang KM, Shemesh A, Punzalan EB, Sarma A, Calfee CS, Christenson SA, Langelier CR, Hays SR, Golden JA, Leard LE, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Lanier LL, Greenland JR, Sayah DM, Ardehali A, Kukreja J, Weigt SS, Belperio JA, Singer JP, Looney MR. PMID: 36346670; PMCID: PMC9869973.
52. Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure. Respir Res. 2022 Dec 16; 23(1):354.Ghale R, Spottiswoode N, Anderson MS, Mitchell A, Wang G, Calfee CS, DeRisi JL, Langelier CR. PMID: 36527083; PMCID: PMC9756918.
53. Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome. Annu Rev Med. 2023 01 27; 74:457-471.Sinha P, Meyer NJ, Calfee CS. PMID: 36469902; PMCID: PMC10617629.
54. Immune Modulation in Sepsis, ARDS, and Covid-19 - The Road Traveled and the Road Ahead. NEJM Evid. 2022 Nov; 1(11):EVIDra2200118.Leligdowicz A, Harhay MO, Calfee CS. PMID: 38319856.
55. Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults. Nat Microbiol. 2022 11; 7(11):1805-1816.Kalantar KL, Neyton L, Abdelghany M, Mick E, Jauregui A, Caldera S, Serpa PH, Ghale R, Albright J, Sarma A, Tsitsiklis A, Leligdowicz A, Christenson SA, Liu K, Kangelaris KN, Hendrickson C, Sinha P, Gomez A, Neff N, Pisco A, Doernberg SB, Derisi JL, Matthay MA, Calfee CS, Langelier CR. PMID: 36266337; PMCID: PMC9613463.
56. COVID-19-associated Lung Microvascular Endotheliopathy: A "From the Bench" Perspective. Am J Respir Crit Care Med. 2022 10 15; 206(8):961-972.Joffre J, Rodriguez L, Matthay ZA, Lloyd E, Fields AT, Bainton RJ, Kurien P, Sil A, Calfee CS, Woodruff PG, Erle DJ, Hendrickson C, Krummel MF, Langelier CR, Matthay MA, Kornblith LZ, Hellman J, COVID-19 Multi-Phenotyping for Effective Therapies (COMET) Consortium, COVID-19 Associated Coagulopathy, Inflammation, and Thrombosis (Co-ACIT) Study Group. PMID: 35649173; PMCID: PMC9801996.
57. Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia. EBioMedicine. 2022 Nov; 85:104295.Lyons PG, Bhavani SV, Mody A, Bewley A, Dittman K, Doyle A, Windham SL, Patel TM, Raju BN, Keller M, Churpek MM, Calfee CS, Michelson AP, Kannampallil T, Geng EH, Sinha P. PMID: 36202054; PMCID: PMC9527494.
58. Informed consent process in the ISPY COVID trial is ethically acceptable. Eur J Intern Med. 2023 01; 107:97.Files DC, Esserman L, Liu KD, Calfee CS. PMID: 36184277.
59. Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19. Crit Care. 2022 09 14; 26(1):278.Wick KD, Leligdowicz A, Willmore A, Carrillo SA, Ghale R, Jauregui A, Chak SS, Nguyen V, Lee D, Jones C, Dewar R, Lane HC, Kangelaris KN, Hendrickson CM, Liu KD, Sinha P, Erle DJ, Langelier CR, Krummell MF, Woodruff PG, Calfee CS, Matthay MA, COMET Consortium. PMID: 36104754; PMCID: PMC9472195.
60. The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial. Crit Care Resusc. 2022 Sep 05; 24(3):251-258.McKelvey MC, Bradbury I, McDowell C, Calfee CS, Weldon S, O'Kane CM, McAuley DF, Taggart CC. PMID: 38046206; PMCID: PMC10692599.
61. New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021. Am J Respir Cell Mol Biol. 2022 09; 67(3):284-308.Martin TR, Zemans RL, Ware LB, Schmidt EP, Riches DWH, Bastarache L, Calfee CS, Desai TJ, Herold S, Hough CL, Looney MR, Matthay MA, Meyer N, Parikh SM, Stevens T, Thompson BT. PMID: 35679511; PMCID: PMC9447141.
62. Contemporary trends in PGD incidence, outcomes, and therapies. J Heart Lung Transplant. 2022 12; 41(12):1839-1849.Cantu E, Diamond JM, Cevasco M, Suzuki Y, Crespo M, Clausen E, Dallara L, Ramon CV, Harmon MT, Bermudez C, Benvenuto L, Anderson M, Wille KM, Weinacker A, Dhillon GS, Orens J, Shah P, Merlo C, Lama V, McDyer J, Snyder L, Palmer S, Hartwig M, Hage CA, Singer J, Calfee C, Kukreja J, Greenland JR, Ware LB, Localio R, Hsu J, Gallop R, Christie JD. PMID: 36216694; PMCID: PMC9990084.
63. Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study. EBioMedicine. 2022 Sep; 83:104208.Ozonoff A, Schaenman J, Jayavelu ND, Milliren CE, Calfee CS, Cairns CB, Kraft M, Baden LR, Shaw AC, Krammer F, van Bakel H, Esserman DA, Liu S, Sesma AF, Simon V, Hafler DA, Montgomery RR, Kleinstein SH, Levy O, Bime C, Haddad EK, Erle DJ, Pulendran B, Nadeau KC, Davis MM, Hough CL, Messer WB, Higuita NIA, Metcalf JP, Atkinson MA, Brakenridge SC, Corry D, Kheradmand F, Ehrlich LIR, Melamed E, McComsey GA, Sekaly R, Diray-Arce J, Peters B, Augustine AD, Reed EF, Altman MC, Becker PM, Rouphael N, IMPACC study group members. PMID: 35952496; PMCID: PMC9359694.
64. Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections. Genome Med. 2022 07 12; 14(1):74.Serpa PH, Deng X, Abdelghany M, Crawford E, Malcolm K, Caldera S, Fung M, McGeever A, Kalantar KL, Lyden A, Ghale R, Deiss T, Neff N, Miller SA, Doernberg SB, Chiu CY, DeRisi JL, Calfee CS, Langelier CR. PMID: 35818068; PMCID: PMC9275031.
65. Redefining critical illness. Nat Med. 2022 06; 28(6):1141-1148.Maslove DM, Tang B, Shankar-Hari M, Lawler PR, Angus DC, Baillie JK, Baron RM, Bauer M, Buchman TG, Calfee CS, Dos Santos CC, Giamarellos-Bourboulis EJ, Gordon AC, Kellum JA, Knight JC, Leligdowicz A, McAuley DF, McLean AS, Menon DK, Meyer NJ, Moldawer LL, Reddy K, Reilly JP, Russell JA, Sevransky JE, Seymour CW, Shapiro NI, Singer M, Summers C, Sweeney TE, Thompson BT, van der Poll T, Venkatesh B, Walley KR, Walsh TS, Ware LB, Wong HR, Zador ZE, Marshall JC. PMID: 35715504.
66. Extracorporeal Membrane Oxygenation during Respiratory Pandemics: Past, Present, and Future. Am J Respir Crit Care Med. 2022 06 15; 205(12):1382-1390.Brodie D, Abrams D, MacLaren G, Brown CE, Evans L, Barbaro RP, Calfee CS, Hough CL, Fowles JA, Karagiannidis C, Slutsky AS, Combes A. PMID: 35213298; PMCID: PMC9875895.
67. Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients. Immunity. 2022 07 12; 55(7):1284-1298.e3.Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Munoz Sandoval P, Willmore A, UCSF COMET Consortium, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Calfee CS, Erle DJ, Ansel KM, Spitzer MH. PMID: 35779527; PMCID: PMC9170540.
68. Impact of e-cigarette aerosol on primary human alveolar epithelial type 2 cells. Am J Physiol Lung Cell Mol Physiol. 2022 08 01; 323(2):L152-L164.Wick KD, Fang X, Maishan M, Matsumoto S, Spottiswoode N, Sarma A, Simoneau C, Khakoo M, Langelier C, Calfee CS, Gotts JE, Matthay MA. PMID: 35670478; PMCID: PMC9559034.
69. I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations. BMJ Open. 2022 06 06; 12(6):e060664.Files DC, Matthay MA, Calfee CS, Aggarwal NR, Asare AL, Beitler JR, Berger PA, Burnham EL, Cimino G, Coleman MH, Crippa A, Discacciati A, Gandotra S, Gibbs KW, Henderson PT, Ittner CAG, Jauregui A, Khan KT, Koff JL, Lang J, LaRose M, Levitt J, Lu R, McKeehan JD, Meyer NJ, Russell DW, Thomas KW, Eklund M, Esserman LJ, Liu KD, ISPY COVID Adaptive Platform Trial Network, undefined. PMID: 35667714; PMCID: PMC9170797.
70. Ventilatory Ratio Is a Valuable Prognostic Indicator in an Observational Cohort of Patients With ARDS. Respir Care. 2022 09; 67(9):1075-1081.Siegel ER, Zhuo H, Sinha P, Papolos AI, Ni SA, Vessel K, Belzer A, Minus EB, Calfee CS, Matthay MA, Wick KD. PMID: 35641002; PMCID: PMC9994339.
71. Immediate myeloid depot for SARS-CoV-2 in the human lung. Res Sq. 2022 May 17.Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH, UCSF COMET Consortium, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. PMID: 35611333; PMCID: PMC9128787.
72. Immediate myeloid depot for SARS-CoV-2 in the human lung. bioRxiv. 2022 May 11.Magnen M, You R, Rao AA, Davis RT, Rodriguez L, Simoneau CR, Hysenaj L, Hu KH, UCSF COMET Consortium, Love C, Woodruff PG, Erle DJ, Hendrickson CM, Calfee CS, Matthay MA, Roose JP, Sil A, Ott M, Langelier CR, Krummel MF, Looney MR. PMID: 35592107; PMCID: PMC9119017.
73. Cigarette Smoke Exposure and Acute Respiratory Distress Syndrome in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. Am J Respir Crit Care Med. 2022 04 15; 205(8):927-935.Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. PMID: 35050845; PMCID: PMC9838633.
74. Prognostic factors for development of acute respiratory distress syndrome following traumatic injury: a systematic review and meta-analysis. Eur Respir J. 2022 04; 59(4).Tran A, Fernando SM, Brochard LJ, Fan E, Inaba K, Ferguson ND, Calfee CS, Burns KEA, Brodie D, McCredie VA, Kim DY, Kyeremanteng K, Lampron J, Slutsky AS, Combes A, Rochwerg B. PMID: 34625477.
75. Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages. Am J Physiol Lung Cell Mol Physiol. 2022 06 01; 322(6):L771-L783.Matsumoto S, Traber MG, Leonard SW, Choi J, Fang X, Maishan M, Wick KD, Jones KD, Calfee CS, Gotts JE, Matthay MA. PMID: 35318859; PMCID: PMC9109788.
76. A conserved immune trajectory of recovery in hospitalized COVID-19 patients. bioRxiv. 2022 Mar 16.Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Sandoval PM, UCSF COMET Consortium, Calfee CS, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Erle DJ, Ansel KM, Spitzer MH. PMID: 35313585; PMCID: PMC8936097.
77. Towards a biological definition of ARDS: are treatable traits the solution? Intensive Care Med Exp. 2022 Mar 11; 10(1):8.Bos LDJ, Laffey JG, Ware LB, Heijnen NFL, Sinha P, Patel B, Jabaudon M, Bastarache JA, McAuley DF, Summers C, Calfee CS, Shankar-Hari M. PMID: 35274164; PMCID: PMC8913033.
78. Pulmonary and Critical Care Considerations for e-Cigarette, or Vaping, Product Use-Associated Lung Injury. Chest. 2022 07; 162(1):256-264.Hayes D, Board A, Calfee CS, Ellington S, Pollack LA, Kathuria H, Eakin MN, Weissman DN, Callahan SJ, Esper AM, Crotty Alexander LE, Sharma NS, Meyer NJ, Smith LS, Novosad S, Evans ME, Goodman AB, Click ES, Robinson RT, Ewart G, Twentyman E. PMID: 35257738.
79. Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness. Crit Care Med. 2022 03 01; 50(3):e284-e293.Mikacenic C, Bhatraju P, Robinson-Cohen C, Kosamo S, Fohner AE, Dmyterko V, Long SA, Cerosaletti K, Calfee CS, Matthay MA, Walley KR, Russell JA, Christie JD, Meyer NJ, Christiani DC, Wurfel MM. PMID: 34593707; PMCID: PMC8863632.
80. Reply to Kuindersma and Spronk: Time to Tailor the One-Size-Fits-All Approach? Am J Respir Crit Care Med. 2022 02 15; 205(4):480-481.Furfaro DM, Sinha P, Calfee CS, Brodie D, O'Donnell MR. PMID: 34818142; PMCID: PMC8886940.
81. Phenotyping in acute respiratory distress syndrome: state of the art and clinical implications. Curr Opin Crit Care. 2022 02 01; 28(1):1-8.Alipanah N, Calfee CS. PMID: 34670998; PMCID: PMC8782441.
82. Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2022 02; 66(2):e1-e14.Kulkarni HS, Lee JS, Bastarache JA, Kuebler WM, Downey GP, Albaiceta GM, Altemeier WA, Artigas A, Bates JHT, Calfee CS, Dela Cruz CS, Dickson RP, Englert JA, Everitt JI, Fessler MB, Gelman AE, Gowdy KM, Groshong SD, Herold S, Homer RJ, Horowitz JC, Hsia CCW, Kurahashi K, Laubach VE, Looney MR, Lucas R, Mangalmurti NS, Manicone AM, Martin TR, Matalon S, Matthay MA, McAuley DF, McGrath-Morrow SA, Mizgerd JP, Montgomery SA, Moore BB, Noël A, Perlman CE, Reilly JP, Schmidt EP, Skerrett SJ, Suber TL, Summers C, Suratt BT, Takata M, Tuder R, Uhlig S, Witzenrath M, Zemans RL, Matute-Bello G. PMID: 35103557; PMCID: PMC8845128.
83. Functional Transcriptomic Studies of Immune Responses and Endotoxin Tolerance in Early Human Sepsis. Shock. 2022 06 01; 57(6):180-190.Leligdowicz A, Kamm J, Kalantar K, Jauregui A, Vessel K, Caldera S, Serpa PH, Abbott J, Fang X, Tian X, Prakash A, Kangelaris KN, Liu KD, Calfee CS, Langelier C, Matthay MA. PMID: 35066510; PMCID: PMC9246838.
84. Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis. Lancet Respir Med. 2022 04; 10(4):367-377.Maddali MV, Churpek M, Pham T, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P, LUNG SAFE Investigators and the ESICM Trials Group. PMID: 35026177; PMCID: PMC8976729.
85. Clinical trial design during and beyond the pandemic: the I-SPY COVID trial. Nat Med. 2022 01; 28(1):9-11.I-SPY COVID Consortium. PMID: 35058620; PMCID: PMC8922451.
86. Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis. Lancet Respir Med. 2022 03; 10(3):289-297.Dahmer MK, Yang G, Zhang M, Quasney MW, Sapru A, Weeks HM, Sinha P, Curley MAQ, Delucchi KL, Calfee CS, Flori H, RESTORE and BALI study investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. PMID: 34883088; PMCID: PMC8897230.
87. Comparison of machine learning clustering algorithms for detecting heterogeneity of treatment effect in acute respiratory distress syndrome: A secondary analysis of three randomised controlled trials. EBioMedicine. 2021 Dec; 74:103697.Sinha P, Spicer A, Delucchi KL, McAuley DF, Calfee CS, Churpek MM. PMID: 34861492; PMCID: PMC8645454.
88. Latent Class Analysis Reveals COVID-19-related Acute Respiratory Distress Syndrome Subgroups with Differential Responses to Corticosteroids. Am J Respir Crit Care Med. 2021 12 01; 204(11):1274-1285.Sinha P, Furfaro D, Cummings MJ, Abrams D, Delucchi K, Maddali MV, He J, Thompson A, Murn M, Fountain J, Rosen A, Robbins-Juarez SY, Adan MA, Satish T, Madhavan M, Gupta A, Lyashchenko AK, Agerstrand C, Yip NH, Burkart KM, Beitler JR, Baldwin MR, Calfee CS, Brodie D, O'Donnell MR. PMID: 34543591; PMCID: PMC8786071.
89. Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19. medRxiv. 2021 Nov 30.Tsitsiklis A, Zha BS, Byrne A, DeVoe C, Rackaityte E, Levan S, Sunshine S, Mick E, Ghale R, Love C, Tarashansky AJ, Pisco A, Albright J, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Detweiler A, Jones NG, Wu B, Darmanis S, Lynch SV, DeRisi JL, COMET Consortium, Matthay MA, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. PMID: 33791731; PMCID: PMC8010763.
90. Promises and challenges of personalized medicine to guide ARDS therapy. Crit Care. 2021 11 23; 25(1):404.Wick KD, McAuley DF, Levitt JE, Beitler JR, Annane D, Riviello ED, Calfee CS, Matthay MA. PMID: 34814925; PMCID: PMC8609268.
91. Metabolic signatures of ARDS and ARDS heterogeneity. Am J Physiol Lung Cell Mol Physiol. 2021 12 01; 321(6):L1067-L1068.Neyton L, Calfee CS. PMID: 34668417; PMCID: PMC8715022.
92. A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2021 10 15; 204(8):891-901.Shah FA, Meyer NJ, Angus DC, Awdish R, Azoulay É, Calfee CS, Clermont G, Gordon AC, Kwizera A, Leligdowicz A, Marshall JC, Mikacenic C, Sinha P, Venkatesh B, Wong HR, Zampieri FG, Yende S. PMID: 34652268; PMCID: PMC8534611.
93. Titrating Oxygen Therapy in Critically Ill Patients. JAMA. 2021 09 14; 326(10):911-913.Urner M, Calfee CS, Fan E. PMID: 34463699.
94. Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01. EClinicalMedicine. 2021 Oct; 40:101099.Weiner J, Suwalski P, Holtgrewe M, Rakitko A, Thibeault C, Müller M, Patriki D, Quedenau C, Krüger U, Ilinsky V, Popov I, Balnis J, Jaitovich A, Helbig ET, Lippert LJ, Stubbemann P, Real LM, Macías J, Pineda JA, Fernandez-Fuertes M, Wang X, Karadeniz Z, Saccomanno J, Doehn JM, Hübner RH, Hinzmann B, Salvo M, Blueher A, Siemann S, Jurisic S, Beer JH, Rutishauser J, Wiggli B, Schmid H, Danninger K, Binder R, Corman VM, Mühlemann B, Arjun Arkal R, Fragiadakis GK, Mick E, Comet C, Calfee CS, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Langelier CR, Venkataramani U, García F, Zyla J, Drosten C, Alice B, Jones TC, Suttorp N, Witzenrath M, Hippenstiel S, Zemojtel T, Skurk C, Poller W, Borodina T, Pa-Covid SG, Ripke S, Sander LE, Beule D, Landmesser U, Guettouche T, Kurth F, Heidecker B. PMID: 34490415; PMCID: PMC8410317.
95. Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS. Nat Commun. 2021 08 26; 12(1):5152.Sarma A, Christenson SA, Byrne A, Mick E, Pisco AO, DeVoe C, Deiss T, Ghale R, Zha BS, Tsitsiklis A, Jauregui A, Moazed F, Detweiler AM, Spottiswoode N, Sinha P, Neff N, Tan M, Serpa PH, Willmore A, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA, COMET Consortium, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR. PMID: 34446707; PMCID: PMC8390461.
96. Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19. Sci Transl Med. 2021 Sep 22; 13(612):eabh2624.van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ, UCSF COMET consortium. PMID: 34429372; PMCID: PMC8601717.
97. Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 Aug; 596(7872):E8.Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, UCSF COMET Consortium, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 34341540; PMCID: PMC8328349.
98. Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids. Crit Care Explor. 2021 Aug; 3(8):e0478.Rogers AJ, Leligdowicz A, Contrepois K, Jauregui A, Vessel K, Deiss TJ, Belzer A, Liu T, Lippi M, Ke S, Ross E, Zhou H, Hendrickson C, Gomez A, Sinha P, Kangelaris KN, Liu KD, Calfee CS, Matthay MA. PMID: 34345827; PMCID: PMC8323800.
99. Advancing precision medicine for acute respiratory distress syndrome. Lancet Respir Med. 2022 01; 10(1):107-120.Beitler JR, Thompson BT, Baron RM, Bastarache JA, Denlinger LC, Esserman L, Gong MN, LaVange LM, Lewis RJ, Marshall JC, Martin TR, McAuley DF, Meyer NJ, Moss M, Reineck LA, Rubin E, Schmidt EP, Standiford TJ, Ware LB, Wong HR, Aggarwal NR, Calfee CS. PMID: 34310901; PMCID: PMC8302189.
100. Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study. Thorax. 2022 01; 77(1):13-21.Sinha P, Delucchi KL, Chen Y, Zhuo H, Abbott J, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Calfee CS. PMID: 34253679; PMCID: PMC8688287.
101. Acute respiratory distress syndrome. Lancet. 2021 08 14; 398(10300):622-637.Meyer NJ, Gattinoni L, Calfee CS. PMID: 34217425; PMCID: PMC8248927.
102. Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS. Eur Respir J. 2021 07; 58(1).Dutra Silva J, Su Y, Calfee CS, Delucchi KL, Weiss D, McAuley DF, O'Kane C, Krasnodembskaya AD. PMID: 33334945; PMCID: PMC8318599.
103. Acute Respiratory Distress Syndrome Subphenotypes beyond the Syndrome: A Step toward Treatable Traits? Am J Respir Crit Care Med. 2021 06 15; 203(12):1449-1451.Reddy K, Calfee CS, McAuley DF. PMID: 33565943; PMCID: PMC8483225.
104. Six-month and 12-month patient outcomes based on inflammatory subphenotypes in sepsis-associated ARDS: secondary analysis of SAILS-ALTOS trial. Thorax. 2022 01; 77(1):22-30.Hashem MD, Hopkins RO, Colantuoni E, Dinglas VD, Sinha P, Aronson Friedman L, Morris PE, Jackson JC, Hough CL, Calfee CS, Needham DM. PMID: 34112703; PMCID: PMC8660939.
105. Accuracy of the Radiographic Assessment of Lung Edema Score for the Diagnosis of ARDS. Front Physiol. 2021; 12:672823.Zimatore C, Pisani L, Lippolis V, Warren MA, Calfee CS, Ware LB, Algera AG, Smit MR, Grasso S, Schultz MJ. PMID: 34122143; PMCID: PMC8188799.
106. Immunotherapy in COVID-19: why, who, and when? Lancet Respir Med. 2021 06; 9(6):549-551.Sinha P, Calfee CS. PMID: 34015326; PMCID: PMC8128672.
107. Sepsis Subclasses: A Framework for Development and Interpretation. Crit Care Med. 2021 05 01; 49(5):748-759.DeMerle KM, Angus DC, Baillie JK, Brant E, Calfee CS, Carcillo J, Chang CH, Dickson R, Evans I, Gordon AC, Kennedy J, Knight JC, Lindsell CJ, Liu V, Marshall JC, Randolph AG, Scicluna BP, Shankar-Hari M, Shapiro NI, Sweeney TE, Talisa VB, Tang B, Thompson BT, Tsalik EL, van der Poll T, van Vught LA, Wong HR, Yende S, Zhao H, Seymour CW. PMID: 33591001; PMCID: PMC8627188.
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109. Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome. Thorax. 2021 11; 76(11):1099-1107.Mac Sweeney R, Reddy K, Davies JC, Parker M, Kelly B, Elborn JS, Conlon J, Verghis RM, Calfee CS, Matthay MA, Alton EWFW, McAuley DF. PMID: 33888572.
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113. Assessing the importance of interleukin-6 in COVID-19 - Authors' reply. Lancet Respir Med. 2021 02; 9(2):e14-e15.Leisman DE, Ronner L, Pinotti R, Taylor MD, Sinha P, Calfee CS, Hirayama AV, Mastroianni F, Turtle CJ, Harhay MO, Legrand M, Deutschman CS. PMID: 33460572; PMCID: PMC7834405.
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123. Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users. J Am Heart Assoc. 2020 12; 9(23):e017317.Benowitz NL, St Helen G, Nardone N, Addo N, Zhang JJ, Harvanko AM, Calfee CS, Jacob P. PMID: 33208019; PMCID: PMC7763797.
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125. Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses. Nat Commun. 2020 11 17; 11(1):5854.Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Castañeda G, DeRisi JL, Detweiler AM, Hao SL, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Calfee CS, Christenson SA, Kistler A, Langelier C. PMID: 33203890; PMCID: PMC7673985.
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127. Prone Positioning in Awake, Nonintubated Patients With COVID-19: Necessity Is the Mother of Invention. JAMA Intern Med. 2020 11 01; 180(11):1539-1540.Sarma A, Calfee CS. PMID: 32584940.
128. Global Absence and Targeting of Protective Immune States in Severe COVID-19. bioRxiv. 2020 Oct 29.Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33140050; PMCID: PMC7605559.
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131. Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020 12 01; 319(6):F979-F987.Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD. PMID: 33044866; PMCID: PMC7792692.
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134. E-Cigarette or Vaping Product Use-associated Lung Injury: Developing a Research Agenda. An NIH Workshop Report. Am J Respir Crit Care Med. 2020 09 15; 202(6):795-802.Crotty Alexander LE, Ware LB, Calfee CS, Callahan SJ, Eissenberg T, Farver C, Goniewicz ML, Jaspers I, Kheradmand F, King TE, Meyer NJ, Mikheev VB, Shields PG, Shihadeh A, Strongin R, Tarran R. PMID: 32243764; PMCID: PMC7491408.
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146. Long-term ozone exposure is positively associated with telomere length in critically ill patients. Environ Int. 2020 08; 141:105780.Wang C, Wolters PJ, Calfee CS, Liu S, Balmes JR, Zhao Z, Koyama T, Ware LB. PMID: 32417614; PMCID: PMC7535086.
147. Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis. Respir Res. 2020 Apr 07; 21(1):81.Carla A, Pereira B, Boukail H, Audard J, Pinol-Domenech N, De Carvalho M, Blondonnet R, Zhai R, Morand D, Lambert C, Sapin V, Ware LB, Calfee CS, Bastarache JA, Laffey JG, Juffermans NP, Bos LD, Artigas A, Rocco PRM, Matthay MA, McAuley DF, Constantin JM, Jabaudon M, ESICM Translational Biology Group of the Acute Respiratory Failure section. PMID: 32264897; PMCID: PMC7137453.
148. Gender Differences in Authorship of Critical Care Literature. Am J Respir Crit Care Med. 2020 04 01; 201(7):840-847.Vranas KC, Ouyang D, Lin AL, Slatore CG, Sullivan DR, Kerlin MP, Liu KD, Baron RM, Calfee CS, Ware LB, Halpern SD, Matthay MA, Herridge MS, Mehta S, Rogers AJ. PMID: 31968182; PMCID: PMC7124723.
149. ARDS Subphenotypes: Understanding a Heterogeneous Syndrome. Crit Care. 2020 Mar 24; 24(1):102.Wilson JG, Calfee CS. PMID: 32204722; PMCID: PMC7092435.
150. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. Intensive Care Med. 2020 06; 46(6):1222-1231.Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS. PMID: 32206845; PMCID: PMC7224051.
151. Lack of Clinical Benefit of Interferon β-1a Among Patients With Severe Acute Respiratory Distress Syndrome: Time to Overhaul Drug Trials in ARDS? JAMA. 2020 02 25; 323(8):713-715.Shankar-Hari M, Calfee CS. PMID: 32065830.
152. Detection of Pneumonia Pathogens from Plasma Cell-Free DNA. Am J Respir Crit Care Med. 2020 02 15; 201(4):491-495.Langelier C, Fung M, Caldera S, Deiss T, Lyden A, Prince BC, Serpa PH, Moazed F, Chin-Hong P, DeRisi JL, Calfee CS. PMID: 31647702; PMCID: PMC7049928.
153. Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Crit Care Med. 2020 02; 48(2):200-209.Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN. PMID: 31939788; PMCID: PMC7494056.
154. Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. Eur Respir J. 2020 01; 55(1).Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ. PMID: 31619475; PMCID: PMC7359873.
155. Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials. Lancet Respir Med. 2020 03; 8(3):247-257.Sinha P, Delucchi KL, McAuley DF, O'Kane CM, Matthay MA, Calfee CS. PMID: 31948926; PMCID: PMC7543720.
156. Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020 01 01; 201(1):47-56.Jones TK, Feng R, Kerchberger VE, Reilly JP, Anderson BJ, Shashaty MGS, Wang F, Dunn TG, Riley TR, Abbott J, Ittner CAG, Christiani DC, Mikacenic C, Wurfel MM, Ware LB, Calfee CS, Matthay MA, Christie JD, Meyer NJ. PMID: 31487195; PMCID: PMC6938154.
157. Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study. Crit Care. 2019 12 09; 23(1):400.Anderson BJ, Calfee CS, Liu KD, Reilly JP, Kangelaris KN, Shashaty MGS, Lazaar AL, Bayliffe AI, Gallop RJ, Miano TA, Dunn TG, Johansson E, Abbott J, Jauregui A, Deiss T, Vessel K, Belzer A, Zhuo H, Matthay MA, Meyer NJ, Christie JD. PMID: 31818332; PMCID: PMC6902425.
158. Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS. Ann Intensive Care. 2019 Nov 21; 9(1):128.Morales-Quinteros L, Schultz MJ, Bringué J, Calfee CS, Camprubí M, Cremer OL, Horn J, van der Poll T, Sinha P, Artigas A, Bos LD, MARS Consortium. PMID: 31754866; PMCID: PMC6872683.
159. Biomarkers and Precision Medicine: State of the Art. Crit Care Clin. 2020 Jan; 36(1):155-165.Sarma A, Calfee CS, Ware LB. PMID: 31733677.
160. Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice. Am J Physiol Lung Cell Mol Physiol. 2019 11 01; 317(5):L717-L736.Gotts JE, Bernard O, Chun L, Croze RH, Ross JT, Nesseler N, Wu X, Abbott J, Fang X, Calfee CS, Matthay MA. PMID: 31509438; PMCID: PMC6879898.
161. FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences. Nucleic Acids Res. 2019 08 22; 47(14):e83.Quan J, Langelier C, Kuchta A, Batson J, Teyssier N, Lyden A, Caldera S, McGeever A, Dimitrov B, King R, Wilheim J, Murphy M, Ares LP, Travisano KA, Sit R, Amato R, Mumbengegwi DR, Smith JL, Bennett A, Gosling R, Mourani PM, Calfee CS, Neff NF, Chow ED, Kim PS, Greenhouse B, DeRisi JL, Crawford ED. PMID: 31114866; PMCID: PMC6698650.
162. A new frontier in ARDS trials: phenotyping before randomisation. Lancet Respir Med. 2019 10; 7(10):830-831.Hendrickson CM, Calfee CS. PMID: 31399380.
163. Inflammasomes Assemble: Cytoplasmic Guardians or Fallen Heroes? Crit Care Med. 2019 08; 47(8):1161-1163.Sinha P, Calfee CS. PMID: 31305304; PMCID: PMC7043370.
164. Predictors of postinjury acute respiratory distress syndrome: Lung injury persists in the era of hemostatic resuscitation. J Trauma Acute Care Surg. 2019 08; 87(2):371-378.Kornblith LZ, Robles AJ, Conroy AS, Redick BJ, Howard BM, Hendrickson CM, Moore S, Nelson MF, Moazed F, Callcut RA, Calfee CS, Cohen MJ. PMID: 31033882; PMCID: PMC6660388.
165. Peeking under the Hood of Acute Respiratory Distress Syndrome Phenotypes: Deeper Insights into Biological Heterogeneity. Am J Respir Crit Care Med. 2019 Jul 01; 200(1):4-6.Sinha P, Calfee CS. PMID: 30753791; PMCID: PMC6603053.
166. Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction. Respir Care. 2019 Sep; 64(9):1101-1108.Papolos AI, Schiller NB, Belzer A, Zhuo H, Gotts JE, Bibby D, Calfee CS, Matthay MA. PMID: 31138736.
167. Acute Respiratory Distress Syndrome Phenotypes. Semin Respir Crit Care Med. 2019 02; 40(1):19-30.Reilly JP, Calfee CS, Christie JD. PMID: 31060085; PMCID: PMC6657496.
168. Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply. Lancet Respir Med. 2019 04; 7(4):e14.Matthay MA, Zhuo H, Gotts JE, Liu KD, Calfee CS. PMID: 30926051.
169. The authors reply. Crit Care Med. 2019 04; 47(4):e375-e376.Fielding-Singh V, Matthay MA, Calfee CS. PMID: 30882440; PMCID: PMC6467538.
170. The authors reply. Crit Care Med. 2019 04; 47(4):e380-e381.Fielding-Singh V, Matthay MA, Calfee CS. PMID: 30882446; PMCID: PMC6494106.
171. Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy. Am J Respir Crit Care Med. 2019 04 01; 199(7):863-872.Bhatraju PK, Zelnick LR, Herting J, Katz R, Mikacenic C, Kosamo S, Morrell ED, Robinson-Cohen C, Calfee CS, Christie JD, Liu KD, Matthay MA, Hahn WO, Dmyterko V, Slivinski NSJ, Russell JA, Walley KR, Christiani DC, Liles WC, Himmelfarb J, Wurfel MM. PMID: 30334632; PMCID: PMC6444649.
172. Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury. Pediatr Crit Care Med. 2019 04; 20(4):323-331.Zinter MS, Spicer AC, Liu KD, Orwoll BE, Alkhouli MF, Brakeman PR, Calfee CS, Matthay MA, Sapru A. PMID: 30672838; PMCID: PMC6454886.
173. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019 03 14; 5(1):18.Matthay MA, Zemans RL, Zimmerman GA, Arabi YM, Beitler JR, Mercat A, Herridge M, Randolph AG, Calfee CS. PMID: 30872586; PMCID: PMC6709677.
174. Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure. Ann Am Thorac Soc. 2019 03; 16(3):356-362.Lanspa MJ, Gong MN, Schoenfeld DA, Lee KT, Grissom CK, Hou PC, Serpa-Neto A, Brown SM, Iwashyna TJ, Yealy DM, Hough CL, Brower RG, Calfee CS, Hyzy RC, Matthay MA, Miller RR, Steingrub JS, Thompson BT, Miller CD, Clemmer TP, Hendey GW, Huang DT, Mathews KS, Qadir N, Tidswell M, The National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (P. PMID: 30407869; PMCID: PMC6394119.
175. Phenotypes in acute respiratory distress syndrome: moving towards precision medicine. Curr Opin Crit Care. 2019 02; 25(1):12-20.Sinha P, Calfee CS. PMID: 30531367; PMCID: PMC6814152.
176. Physiologic Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2019 02 01; 199(3):333-341.Sinha P, Calfee CS, Beitler JR, Soni N, Ho K, Matthay MA, Kallet RH. PMID: 30211618; PMCID: PMC6363976.
177. Metagenomic comparison of tracheal aspirate and mini-bronchial alveolar lavage for assessment of respiratory microbiota. Am J Physiol Lung Cell Mol Physiol. 2019 03 01; 316(3):L578-L584.Kalantar KL, Moazed F, Christenson SC, Wilson J, Deiss T, Belzer A, Vessel K, Caldera S, Jauregui A, Bolourchi S, DeRisi JL, Calfee CS, Langelier C. PMID: 30652494; PMCID: PMC6459290.
178. Early Plasma Matrix Metalloproteinase Profiles. A Novel Pathway in Pediatric Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2019 01 15; 199(2):181-189.Zinter MS, Delucchi KL, Kong MY, Orwoll BE, Spicer AS, Lim MJ, Alkhouli MF, Ratiu AE, McKenzie AV, McQuillen PS, Dvorak CC, Calfee CS, Matthay MA, Sapru A. PMID: 30114376; PMCID: PMC6353006.
179. Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. Am J Respir Crit Care Med. 2019 01 01; 199(1):62-70.Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB. PMID: 30067389; PMCID: PMC6353017.
180. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults. Proc Natl Acad Sci U S A. 2018 12 26; 115(52):E12353-E12362.Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. PMID: 30482864; PMCID: PMC6310811.
181. Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial. Lancet Respir Med. 2019 02; 7(2):154-162.Matthay MA, Calfee CS, Zhuo H, Thompson BT, Wilson JG, Levitt JE, Rogers AJ, Gotts JE, Wiener-Kronish JP, Bajwa EK, Donahoe MP, McVerry BJ, Ortiz LA, Exline M, Christman JW, Abbott J, Delucchi KL, Caballero L, McMillan M, McKenna DH, Liu KD. PMID: 30455077; PMCID: PMC7597675.
182. Beyond Low Tidal Volume Ventilation: Treatment Adjuncts for Severe Respiratory Failure in Acute Respiratory Distress Syndrome. Crit Care Med. 2018 11; 46(11):1820-1831.Fielding-Singh V, Matthay MA, Calfee CS. PMID: 30247273; PMCID: PMC6277052.
183. Perhaps it's not the platelet: Ristocetin uncovers the potential role of von Willebrand factor in impaired platelet aggregation following traumatic brain injury. J Trauma Acute Care Surg. 2018 11; 85(5):873-880.Kornblith LZ, Robles AJ, Conroy AS, Hendrickson CM, Calfee CS, Fields AT, Callcut RA, Cohen MJ. PMID: 29985231; PMCID: PMC6202182.
184. Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis. Intensive Care Med. 2018 Nov; 44(11):1849-1858.Reilly JP, Wang F, Jones TK, Palakshappa JA, Anderson BJ, Shashaty MGS, Dunn TG, Johansson ED, Riley TR, Lim B, Abbott J, Ittner CAG, Cantu E, Lin X, Mikacenic C, Wurfel MM, Christiani DC, Calfee CS, Matthay MA, Christie JD, Feng R, Meyer NJ. PMID: 30343317; PMCID: PMC6697901.
185. Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study. Intensive Care Med. 2018 Nov; 44(11):1859-1869.Sinha P, Delucchi KL, Thompson BT, McAuley DF, Matthay MA, Calfee CS, NHLBI ARDS Network. PMID: 30291376; PMCID: PMC6317524.
186. Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis. Eur J Anaesthesiol. 2018 09; 35(9):702-709.Serpa Neto A, Bos LD, Campos PPZA, Hemmes SNT, Bluth T, Calfee CS, Ferner M, Güldner A, Hollmann MW, India I, Kiss T, Laufenberg-Feldmann R, Sprung J, Sulemanji D, Unzueta C, Vidal Melo MF, Weingarten TN, Tuip-de Boer AM, Pelosi P, Gama de Abreu M, Schultz MJ, PROVHILO* and the PROVE** investigators. PMID: 29957706.
187. Assessment of industry data on pulmonary and immunosuppressive effects of IQOS. Tob Control. 2018 11; 27(Suppl 1):s20-s25.Moazed F, Chun L, Matthay MA, Calfee CS, Gotts J. PMID: 30158203; PMCID: PMC6252496.
188. Possible hepatotoxicity of IQOS. Tob Control. 2018 11; 27(Suppl 1):s39-s40.Chun L, Moazed F, Matthay M, Calfee C, Gotts J. PMID: 30131373; PMCID: PMC6238953.
189. Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. Lancet Respir Med. 2018 09; 6(9):691-698.Calfee CS, Delucchi KL, Sinha P, Matthay MA, Hackett J, Shankar-Hari M, McDowell C, Laffey JG, O'Kane CM, McAuley DF, Irish Critical Care Trials Group. PMID: 30078618; PMCID: PMC6201750.
190. Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data. Intensive Care Med. 2018 Sep; 44(9):1388-1399.Jabaudon M, Blondonnet R, Pereira B, Cartin-Ceba R, Lichtenstern C, Mauri T, Determann RM, Drabek T, Hubmayr RD, Gajic O, Uhle F, Coppadoro A, Pesenti A, Schultz MJ, Ranieri MV, Brodska H, Mrozek S, Sapin V, Matthay MA, Constantin JM, Calfee CS. PMID: 30051136; PMCID: PMC6132684.
191. Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L638-L644.Leligdowicz A, Chun LF, Jauregui A, Vessel K, Liu KD, Calfee CS, Matthay MA. PMID: 30024307; PMCID: PMC6295506.
192. Health care utilization and the cost of posttraumatic acute respiratory distress syndrome care. J Trauma Acute Care Surg. 2018 07; 85(1):148-154.Robles AJ, Kornblith LZ, Hendrickson CM, Howard BM, Conroy AS, Moazed F, Calfee CS, Cohen MJ, Callcut RA. PMID: 29958249; PMCID: PMC6029709.
193. Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury. Trauma Surg Acute Care Open. 2018; 3(1):e000171.Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ. PMID: 30023434; PMCID: PMC6045722.
194. Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS. Thorax. 2018 09; 73(9):840-846.Warren MA, Zhao Z, Koyama T, Bastarache JA, Shaver CM, Semler MW, Rice TW, Matthay MA, Calfee CS, Ware LB. PMID: 29903755; PMCID: PMC6410734.
195. Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice. Am J Physiol Lung Cell Mol Physiol. 2018 07 01; 315(1):L25-L40.Gotts JE, Chun L, Abbott J, Fang X, Takasaka N, Nishimura SL, Springer ML, Schick SF, Calfee CS, Matthay MA. PMID: 29543040; PMCID: PMC6087899.
196. Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 03 01; 197(5):621-631.Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. PMID: 29035085; PMCID: PMC6005235.
197. Stability of ARDS subphenotypes over time in two randomised controlled trials. Thorax. 2018 05; 73(5):439-445.Delucchi K, Famous KR, Ware LB, Parsons PE, Thompson BT, Calfee CS, ARDS Network. PMID: 29477989; PMCID: PMC6497167.
198. Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury. JCI Insight. 2018 02 08; 3(3).Lefrançais E, Mallavia B, Zhuo H, Calfee CS, Looney MR. PMID: 29415887; PMCID: PMC5821185.
199. Platelet aggregation after blunt trauma is associated with the acute respiratory distress syndrome and altered by cigarette smoke exposure. J Trauma Acute Care Surg. 2018 02; 84(2):365-371.Moazed F, Hendrickson C, Nelson M, Conroy A, Cohen MJ, Calfee CS. PMID: 29140951; PMCID: PMC5780202.
200. Exposing the bidirectional effects of alcohol on coagulation in trauma: Impaired clot formation and decreased fibrinolysis in rotational thromboelastometry. J Trauma Acute Care Surg. 2018 01; 84(1):97-103.Howard BM, Kornblith LZ, Redick BJ, Conroy AS, Nelson MF, Calfee CS, Callcut RA, Cohen MJ. PMID: 29267182; PMCID: PMC6063843.
201. Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties". Am J Physiol Lung Cell Mol Physiol. 2017 11 01; 313(5):L966-L967.Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. PMID: 29109110; PMCID: PMC5792183.
202. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017; 2(1):e000108.Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ. PMID: 29766103; PMCID: PMC5877916.
203. Reply: Next Step to Understanding Subphenotypes of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 09 15; 196(6):796.Calfee CS, Delucchi K, Famous KR. PMID: 28406712; PMCID: PMC5620680.
204. Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice. Nicotine Tob Res. 2017 Sep 01; 19(9):1033-1039.Gotts JE, Abbott J, Fang X, Yanagisawa H, Takasaka N, Nishimura SL, Calfee CS, Matthay MA. PMID: 28340238; PMCID: PMC5896544.
205. Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries. Trauma Surg Acute Care Open. 2017; 2(1):e000121.Ware LB, Zhao Z, Koyama T, Brown RM, Semler MW, Janz DR, May AK, Fremont RD, Matthay MA, Cohen MJ, Calfee CS. PMID: 29766112; PMCID: PMC5887582.
206. Gender Parity in Critical Care Medicine. Am J Respir Crit Care Med. 2017 08 15; 196(4):425-429.Mehta S, Burns KEA, Machado FR, Fox-Robichaud AE, Cook DJ, Calfee CS, Ware LB, Burnham EL, Kissoon N, Marshall JC, Mancebo J, Finfer S, Hartog C, Reinhart K, Maitland K, Stapleton RD, Kwizera A, Amin P, Abroug F, Smith O, Laake JH, Shrestha GS, Herridge MS. PMID: 28240961; PMCID: PMC6995357.
207. External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome. Intensive Care Med. 2017 Aug; 43(8):1123-1131.Zhao Z, Wickersham N, Kangelaris KN, May AK, Bernard GR, Matthay MA, Calfee CS, Koyama T, Ware LB. PMID: 28593401; PMCID: PMC5978765.
208. Characterization of distinct coagulopathic phenotypes in injury: Pathway-specific drivers and implications for individualized treatment. J Trauma Acute Care Surg. 2017 06; 82(6):1055-1062.Christie SA, Kornblith LZ, Howard BM, Conroy AS, Kunitake RC, Nelson MF, Hendrickson CM, Calfee CS, Callcut RA, Cohen MJ. PMID: 28338598; PMCID: PMC6019554.
209. Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. Lancet Respir Med. 2017 06; 5(6):512-523.Meyer NJ, Calfee CS. PMID: 28664850; PMCID: PMC7103930.
210. Pulmonary toxicity of e-cigarettes. Am J Physiol Lung Cell Mol Physiol. 2017 08 01; 313(2):L193-L206.Chun LF, Moazed F, Calfee CS, Matthay MA, Gotts JE. PMID: 28522559; PMCID: PMC5582932.
211. Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2017 May; 45(5):858-866.Zinter MS, Orwoll BE, Spicer AC, Alkhouli MF, Calfee CS, Matthay MA, Sapru A. PMID: 28248715; PMCID: PMC5392136.
212. Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis. Thorax. 2017 10; 72(10):876-883.Bos LD, Schouten LR, van Vught LA, Wiewel MA, Ong DSY, Cremer O, Artigas A, Martin-Loeches I, Hoogendijk AJ, van der Poll T, Horn J, Juffermans N, Calfee CS, Schultz MJ, MARS consortium. PMID: 28450529; PMCID: PMC5964254.
213. The Canary in the Coal Mine Is Coughing: Electronic Cigarettes and Respiratory Symptoms in Adolescents. Am J Respir Crit Care Med. 2017 04 15; 195(8):974-976.Moazed F, Calfee CS. PMID: 28409686; PMCID: PMC5422651.
214. Higher mini-BAL total protein concentration in early ARDS predicts faster resolution of lung injury measured by more ventilator-free days. Am J Physiol Lung Cell Mol Physiol. 2017 05 01; 312(5):L579-L585.Hendrickson CM, Abbott J, Zhuo H, Liu KD, Calfee CS, Matthay MA, NHLBI ARDS Network. PMID: 28213470; PMCID: PMC5451593.
215. Acute Respiratory Distress Syndrome Subphenotypes Respond Differently to Randomized Fluid Management Strategy. Am J Respir Crit Care Med. 2017 02 01; 195(3):331-338.Famous KR, Delucchi K, Ware LB, Kangelaris KN, Liu KD, Thompson BT, Calfee CS, ARDS Network. PMID: 27513822; PMCID: PMC5328179.
216. Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. Crit Care. 2016 11 17; 20(1):372.Bhatraju PK, Mukherjee P, Robinson-Cohen C, O'Keefe GE, Frank AJ, Christie JD, Meyer NJ, Liu KD, Matthay MA, Calfee CS, Christiani DC, Himmelfarb J, Wurfel MM. PMID: 27852290; PMCID: PMC5112626.
217. A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2016 10; 17(10):907-916.Spicer AC, Calfee CS, Zinter MS, Khemani RG, Lo VP, Alkhouli MF, Orwoll BE, Graciano AL, Boriosi JP, Howard JP, Flori HR, Matthay MA, Sapru A. PMID: 27487912; PMCID: PMC5268071.
218. Clinical Predictors of Hospital Mortality Differ Between Direct and Indirect ARDS. Chest. 2017 04; 151(4):755-763.Luo L, Shaver CM, Zhao Z, Koyama T, Calfee CS, Bastarache JA, Ware LB. PMID: 27663180; PMCID: PMC5472517.
219. The authors reply. Crit Care Med. 2016 08; 44(8):e769-70.Kangelaris KN, Ware LB, Matthay MA, Calfee CS. PMID: 27428148; PMCID: PMC5031148.
220. The authors reply. Crit Care Med. 2016 08; 44(8):e771.Kangelaris KN, Ware LB, Matthay MA, Calfee CS. PMID: 27428150; PMCID: PMC5338942.
221. Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design. Am J Respir Crit Care Med. 2016 07 15; 194(2):147-55.Prescott HC, Calfee CS, Thompson BT, Angus DC, Liu VX. PMID: 27244481; PMCID: PMC5003218.
222. Opening the Debate on the New Sepsis Definition. Precision Medicine: An Opportunity to Improve Outcomes of Patients with Sepsis. Am J Respir Crit Care Med. 2016 07 15; 194(2):137-9.Calfee CS. PMID: 27167090; PMCID: PMC5003223.
223. The acute respiratory distress syndrome following isolated severe traumatic brain injury. J Trauma Acute Care Surg. 2016 06; 80(6):989-97.Hendrickson CM, Howard BM, Kornblith LZ, Conroy AS, Nelson MF, Zhuo H, Liu KD, Manley GT, Matthay MA, Calfee CS, Cohen MJ. PMID: 26881489; PMCID: PMC5851280.
224. Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. Crit Care. 2016 May 23; 20(1):151.Sapru A, Liu KD, Wiemels J, Wiemels J, Hansen H, Pawlikowska L, Poon A, Jorgenson E, Witte JS, Calfee CS, Ware LB, Matthay MA, NHLBI ARDS Network. PMID: 27215212; PMCID: PMC4876559.
225. Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2016 May 15; 193(10):1143-50.Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. PMID: 26681363; PMCID: PMC4872663.
226. Personalized medicine for ARDS: the 2035 research agenda. Intensive Care Med. 2016 May; 42(5):756-767.Beitler JR, Goligher EC, Schmidt M, Spieth PM, Zanella A, Martin-Loeches I, Calfee CS, Cavalcanti AB, ARDSne(x)t Investigators. PMID: 27040103; PMCID: PMC4850840.
227. Diagnostic workup for ARDS patients. Intensive Care Med. 2016 May; 42(5):674-685.Papazian L, Calfee CS, Chiumello D, Luyt CE, Meyer NJ, Sekiguchi H, Matthay MA, Meduri GU. PMID: 27007111; PMCID: PMC7080099.
228. Focusing on the alveolar epithelium: Alveolar fluid clearance in diffuse versus focal acute respiratory distress syndrome. Anaesth Crit Care Pain Med. 2016 Apr; 35(2):75-7.Monsel A, Calfee CS. PMID: 26924611.
229. Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation. Thorax. 2016 12; 71(12):1130-1136.Moazed F, Burnham EL, Vandivier RW, O'Kane CM, Shyamsundar M, Hamid U, Abbott J, Thickett DR, Matthay MA, McAuley DF, Calfee CS. PMID: 26839359; PMCID: PMC4970978.
230. The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia. J Heart Lung Transplant. 2016 Apr; 35(4):500-507.Diamond JM, Porteous MK, Roberts LJ, Wickersham N, Rushefski M, Kawut SM, Shah RJ, Cantu E, Lederer DJ, Chatterjee S, Lama VN, Bhorade S, Crespo M, McDyer J, Wille K, Orens J, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Hage C, Palmer SM, Snyder L, Calfee CS, Ware LB, Christie JD, Lung Transplant Outcomes Group. PMID: 26856667; PMCID: PMC4821817.
231. Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Jan; 44(1):120-9.Kangelaris KN, Ware LB, Wang CY, Janz DR, Zhuo H, Matthay MA, Calfee CS. PMID: 26474112; PMCID: PMC4774861.
232. Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study. Crit Care. 2015 Dec 14; 19:435.Orwoll BE, Spicer AC, Zinter MS, Alkhouli MF, Khemani RG, Flori HR, Neuhaus JM, Calfee CS, Matthay MA, Sapru A. PMID: 26652251; PMCID: PMC4699329.
233. Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 01; 310(3):L224-31.Zinter MS, Spicer A, Orwoll BO, Alkhouli M, Dvorak CC, Calfee CS, Matthay MA, Sapru A. PMID: 26660787; PMCID: PMC5504437.
234. ARDS in 2015: new clinical directions, new biological insights. Lancet Respir Med. 2015 Dec; 3(12):912-3.Calfee CS. PMID: 26679016.
235. Interstitial lung diseases in the hospitalized patient. BMC Med. 2015 Sep 25; 13:245.Disayabutr S, Calfee CS, Collard HR, Wolters PJ. PMID: 26407727; PMCID: PMC4584017.
236. Misclassification of acute respiratory distress syndrome after traumatic injury: The cost of less rigorous approaches. J Trauma Acute Care Surg. 2015 Sep; 79(3):417-24.Hendrickson CM, Dobbins S, Redick BJ, Greenberg MD, Calfee CS, Cohen MJ. PMID: 26307875; PMCID: PMC4552075.
237. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med. 2015 Sep; 43(9):1790-7.Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. PMID: 26010690; PMCID: PMC4737582.
238. Biomarkers of ARDS: what's new? Intensive Care Med. 2016 May; 42(5):797-799.Ware LB, Calfee CS. PMID: 26174184.
239. Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest. 2015 Jun; 147(6):1539-1548.Calfee CS, Janz DR, Bernard GR, May AK, Kangelaris KN, Matthay MA, Ware LB. PMID: 26033126; PMCID: PMC4451708.
240. Differences in degree, differences in kind: characterizing lung injury in trauma. J Trauma Acute Care Surg. 2015 Apr; 78(4):735-41.Howard BM, Kornblith LZ, Hendrickson CM, Redick BJ, Conroy AS, Nelson MF, Callcut RA, Calfee CS, Cohen MJ. PMID: 25742257; PMCID: PMC4624341.
241. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS. Am J Physiol Lung Cell Mol Physiol. 2015 Jun 01; 308(11):L1102-13.Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS. PMID: 25795726; PMCID: PMC4451399.
242. Erratum to: plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Med. 2015 Mar; 41(3):574.Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Matthay MA, NHLBI ARDS Network. PMID: 25708422.
243. Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Med. 2015 Mar; 41(3):470-8.Sapru A, Calfee CS, Liu KD, Kangelaris K, Hansen H, Pawlikowska L, Ware LB, Alkhouli MF, Abbott J, Abbot J, Matthay MA, NHLBI ARDS Network. PMID: 25643902; PMCID: PMC4500527.
244. Clearing the air. Smoking and incident asthma in adults. Am J Respir Crit Care Med. 2015 Jan 15; 191(2):123-4.Moazed F, Calfee CS. PMID: 25590151; PMCID: PMC4347441.
245. Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial. Lancet Respir Med. 2015 Jan; 3(1):24-32.Wilson JG, Liu KD, Zhuo H, Caballero L, McMillan M, Fang X, Cosgrove K, Vojnik R, Calfee CS, Lee JW, Rogers AJ, Levitt J, Wiener-Kronish J, Bajwa EK, Leavitt A, McKenna D, Thompson BT, Matthay MA. PMID: 25529339; PMCID: PMC4297579.
246. ARDS: new mechanistic insights, new therapeutic directions. Clin Chest Med. 2014 Dec; 35(4):xv-xvi.Ware LB, Bastarache JA, Calfee CS. PMID: 25453428.
247. Environmental risk factors for acute respiratory distress syndrome. Clin Chest Med. 2014 Dec; 35(4):625-37.Moazed F, Calfee CS. PMID: 25453414; PMCID: PMC4255333.
248. Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. Crit Care Med. 2014 Sep; 42(9):2058-68.Hsieh SJ, Zhuo H, Benowitz NL, Thompson BT, Liu KD, Matthay MA, Calfee CS, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network, National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Network. PMID: 24942512; PMCID: PMC4134734.
249. Donor smoking is associated with pulmonary edema, inflammation and epithelial dysfunction in ex vivo human donor lungs. Am J Transplant. 2014 Oct; 14(10):2295-302.Ware LB, Lee JW, Wickersham N, Nguyen J, Matthay MA, Calfee CS, California Transplant Donor Network. PMID: 25146497; PMCID: PMC4169304.
250. Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15; 307(6):L435-48.Krupa A, Fol M, Rahman M, Stokes KY, Florence JM, Leskov IL, Khoretonenko MV, Matthay MA, Liu KD, Calfee CS, Tvinnereim A, Rosenfield GR, Kurdowska AK. PMID: 25085625; PMCID: PMC4166786.
251. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Ann Intensive Care. 2014; 4:22.Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA. PMID: 25593740; PMCID: PMC4273700.
252. Intensive care unit scoring systems outperform emergency department scoring systems for mortality prediction in critically ill patients: a prospective cohort study. J Intensive Care. 2014; 2:40.Moseson EM, Zhuo H, Chu J, Stein JC, Matthay MA, Kangelaris KN, Liu KD, Calfee CS. PMID: 25960880; PMCID: PMC4424730.
253. Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1520-9.Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O'Kane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay MA, O'Kane CM. PMID: 24716610; PMCID: PMC4226011.
254. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014 Aug; 2(8):611-20.Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA, NHLBI ARDS Network. PMID: 24853585; PMCID: PMC4154544.
255. Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults. J Crit Care. 2014 Oct; 29(5):718-22.Wong HR, Liu KD, Kangelaris KN, Lahni P, Calfee CS. PMID: 24848949; PMCID: PMC4141017.
256. Is there still a role for the lung injury score in the era of the Berlin definition ARDS? Ann Intensive Care. 2014 Feb 18; 4(1):4.Kangelaris KN, Calfee CS, May AK, Zhuo H, Matthay MA, Ware LB. PMID: 24533450; PMCID: PMC3931496.
257. Fibrinogen and platelet contributions to clot formation: implications for trauma resuscitation and thromboprophylaxis. J Trauma Acute Care Surg. 2014 Feb; 76(2):255-6; discussion 262-3.Kornblith LZ, Kutcher ME, Redick BJ, Calfee CS, Vilardi RF, Cohen MJ. PMID: 24458031; PMCID: PMC4238905.
258. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med. 2014 Mar; 40(3):388-96.Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, Bernard GR, Matthay MA, Ware LB, Kangelaris KN. PMID: 24435201; PMCID: PMC3943651.
259. Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebo-controlled trial. Ann Surg. 2014 Jan; 259(1):26-31.Shyamsundar M, McAuley DF, Shields MO, MacSweeney R, Duffy MJ, Johnston JR, McGuigan J, Backman JT, Calfee CS, Matthay MM, Griffiths MJ, McDowell C, Elborn SJ, O'Kane CM. PMID: 23817506.
260. The association between physiologic dead-space fraction and mortality in subjects with ARDS enrolled in a prospective multi-center clinical trial. Respir Care. 2014 Nov; 59(11):1611-8.Kallet RH, Zhuo H, Liu KD, Calfee CS, Matthay MA, National Heart Lung and Blood Institute ARDS Network Investigators. PMID: 24381187; PMCID: PMC4077995.
261. Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. Crit Care. 2013 Oct 24; 17(5):R253.Ware LB, Koyama T, Zhao Z, Janz DR, Wickersham N, Bernard GR, May AK, Calfee CS, Matthay MA. PMID: 24156650; PMCID: PMC4056313.
262. Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury. Ann Intensive Care. 2013 Aug 11; 3(1):25.Brown LM, Calfee CS, Howard JP, Craig TR, Matthay MA, McAuley DF. PMID: 23937970; PMCID: PMC3846630.
263. Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*. Crit Care Med. 2013 Aug; 41(8):1929-37.Levitt JE, Calfee CS, Goldstein BA, Vojnik R, Matthay MA. PMID: 23782966; PMCID: PMC3748809.
264. Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med. 2013 Apr 01; 187(7):736-42.Agrawal A, Matthay MA, Kangelaris KN, Stein J, Chu JC, Imp BM, Cortez A, Abbott J, Liu KD, Calfee CS. PMID: 23328529; PMCID: PMC3678110.
265. Fixing the leak: targeting the vascular endothelium in sepsis. Crit Care. 2012 Nov 21; 16(6):177.Spicer A, Calfee CS. PMID: 23171759; PMCID: PMC3672578.
266. The search for diagnostic markers in sepsis: many miles yet to go. Am J Respir Crit Care Med. 2012 Jul 01; 186(1):2-4.Calfee CS, Pugin J. PMID: 22753680; PMCID: PMC3400993.
267. Clinical evidence of early acute lung injury often precedes the diagnosis of ALI. J Intensive Care Med. 2013 Jul-Aug; 28(4):241-6.Rackley CR, Levitt JE, Zhuo H, Matthay MA, Calfee CS. PMID: 22733725; PMCID: PMC3482421.
268. Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance. Crit Care Med. 2012 Jun; 40(6):1731-7.Calfee CS, Gallagher D, Abbott J, Thompson BT, Matthay MA, NHLBI ARDS Network. PMID: 22610178; PMCID: PMC3601049.
269. Comparison of chest radiograph scoring to lung weight as a quantitative index of pulmonary edema in organ donors. Clin Transplant. 2012 Sep-Oct; 26(5):665-71.Ware LB, Neyrinck A, O'Neal HR, Lee JW, Landeck M, Johnson E, Calfee CS, Matthay MA, California Transplant Donor Network. PMID: 22324977; PMCID: PMC3642873.
270. Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients. Ann Surg. 2012 Feb; 255(2):379-85.Cohen MJ, Call M, Nelson M, Calfee CS, Esmon CT, Brohi K, Pittet JF. PMID: 22133894; PMCID: PMC3549308.
271. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One. 2012; 7(1):e28268.Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, Sevransky J, Lanken PN, May AK, Aplenc R, Maloney JP, Hakonarson H, Trauma ALI SNP Consortium (TASC) investigators. PMID: 22295056; PMCID: PMC3266233.
272. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest. 2012 May; 141(5):1160-1169.Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA, National Heart, Lung, and Blood Institute ARDS Network. PMID: 22207676; PMCID: PMC3342784.
273. A simple classification model for hospital mortality in patients with acute lung injury managed with lung protective ventilation. Crit Care Med. 2011 Dec; 39(12):2645-51.Brown LM, Calfee CS, Matthay MA, Brower RG, Thompson BT, Checkley W, National Institutes of Health Acute Respiratory Distress Syndrome Network Investigators. PMID: 21725235; PMCID: PMC3227537.
274. FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study. Ann Intensive Care. 2011 Jun 14; 1(1):21.Zhang M, Hsu R, Hsu CY, Kordesch K, Nicasio E, Cortez A, McAlpine I, Brady S, Zhuo H, Kangelaris KN, Stein J, Calfee CS, Liu KD. PMID: 21906363; PMCID: PMC3224491.
275. Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med. 2011 Apr; 39(4):711-7.Calfee CS, Ware LB, Glidden DV, Eisner MD, Parsons PE, Thompson BT, Matthay MA, National Heart, Blood, and Lung Institute Acute Respiratory Distress Syndrome Network. PMID: 21283009; PMCID: PMC3260884.
276. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1660-5.Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. PMID: 21471091; PMCID: PMC3136993.
277. ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med. 2011 May 15; 183(10):1344-53.Meyer NJ, Li M, Feng R, Bradfield J, Gallop R, Bellamy S, Fuchs BD, Lanken PN, Albelda SM, Rushefski M, Aplenc R, Abramova H, Atochina-Vasserman EN, Beers MF, Calfee CS, Cohen MJ, Pittet JF, Christiani DC, O'Keefe GE, Ware LB, May AK, Wurfel MM, Hakonarson H, Christie JD. PMID: 21257790; PMCID: PMC3114062.
278. Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med. 2011 Jan; 39(1):40-5.Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. PMID: 20935560; PMCID: PMC3148017.
279. Therapeutic potential of mesenchymal stem cells for severe acute lung injury. Chest. 2010 Oct; 138(4):965-72.Matthay MA, Thompson BT, Read EJ, McKenna DH, Liu KD, Calfee CS, Lee JW. PMID: 20923800; PMCID: PMC2951759.
280. Therapeutic strategies for severe acute lung injury. Crit Care Med. 2010 Aug; 38(8):1644-50.Diaz JV, Brower R, Calfee CS, Matthay MA. PMID: 20562704; PMCID: PMC4526259.
281. Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans. J Trauma. 2010 Jun; 68(6):1273-8.Cohen MJ, Carles M, Brohi K, Calfee CS, Rahn P, Call MS, Chesebro BB, West MA, Pittet JF. PMID: 20539169; PMCID: PMC3531976.
282. Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock. Crit Care Med. 2010 Jun; 38(6):1436-41.Calfee CS, Thompson BT, Parsons PE, Ware LB, Matthay MA, Wong HR. PMID: 20386309; PMCID: PMC3348116.
283. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma. 2010 May; 68(5):1121-7.Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, May AK, Ware LB. PMID: 20038857; PMCID: PMC3347639.
284. Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2010 Jul; 299(1):L3-7.Collard HR, Calfee CS, Wolters PJ, Song JW, Hong SB, Brady S, Ishizaka A, Jones KD, King TE, Matthay MA, Kim DS. PMID: 20418386; PMCID: PMC2904092.
285. Clinical immunology: Culprits with evolutionary ties. Nature. 2010 Mar 04; 464(7285):41-2.Calfee CS, Matthay MA. PMID: 20203598; PMCID: PMC2857339.
286. Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. Crit Care. 2009; 13(6):R174.Cohen MJ, Brohi K, Calfee CS, Rahn P, Chesebro BB, Christiaans SC, Carles M, Howard M, Pittet JF. PMID: 19887013; PMCID: PMC2811903.
287. Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio. Eur Respir J. 2010 Feb; 35(2):331-7.Ware LB, Fremont RD, Bastarache JA, Calfee CS, Matthay MA. PMID: 19741024; PMCID: PMC2819058.
288. Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury. Crit Care Med. 2009 Apr; 37(4):1322-8.Suratt BT, Eisner MD, Calfee CS, Allard JB, Whittaker LA, Engelken DT, Petty JM, Trimarchi T, Gauthier L, Parsons PE, NHLBI Acute Respiratory Distress Syndrome Network. PMID: 19242319; PMCID: PMC2827851.
289. Identification of early acute lung injury at initial evaluation in an acute care setting prior to the onset of respiratory failure. Chest. 2009 Apr; 135(4):936-943.Levitt JE, Bedi H, Calfee CS, Gould MK, Matthay MA. PMID: 19188549; PMCID: PMC2758305.
290. Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury. Chest. 2009 Jun; 135(6):1440-1447.Kropski JA, Fremont RD, Calfee CS, Ware LB. PMID: 19188556; PMCID: PMC2716712.
291. Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs. Chest. 2009 Feb; 135(2):269-275.Briot R, Frank JA, Uchida T, Lee JW, Calfee CS, Matthay MA. PMID: 19017890; PMCID: PMC2714162.
292. Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury. Intensive Care Med. 2009 Feb; 35(2):248-57.Calfee CS, Eisner MD, Parsons PE, Thompson BT, Conner ER, Matthay MA, Ware LB, NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network. PMID: 18670758; PMCID: PMC2790376.
293. Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax. 2008 Dec; 63(12):1083-9.Calfee CS, Ware LB, Eisner MD, Parsons PE, Thompson BT, Wickersham N, Matthay MA, NHLBI ARDS Network. PMID: 18566109; PMCID: PMC2764528.
294. Aerosolized beta-adrenergic agonist therapy reduces pulmonary edema following lung surgery. Chest. 2008 Apr; 133(4):833-5.Matthay MA, Calfee CS. PMID: 18398109.
295. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med. 2007 Oct; 35(10):2243-50.Calfee CS, Eisner MD, Ware LB, Thompson BT, Parsons PE, Wheeler AP, Korpak A, Matthay MA, Acute Respiratory Distress Syndrome Network, National Heart, Lung, and Blood Institute. PMID: 17944012; PMCID: PMC2765812.
296. Biomarkers of lung injury in primary graft dysfunction following lung transplantation. Biomark Med. 2007 Aug; 1(2):285-91.Calfee CS, Ware LB. PMID: 20477403.
297. Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation. J Heart Lung Transplant. 2007 Jul; 26(7):675-80.Calfee CS, Budev MM, Matthay MA, Church G, Brady S, Uchida T, Ishizaka A, Lara A, Ranes JL, deCamp MM, Arroliga AC. PMID: 17613396; PMCID: PMC2741136.
298. Nonventilatory treatments for acute lung injury and ARDS. Chest. 2007 Mar; 131(3):913-920.Calfee CS, Matthay MA. PMID: 17356114; PMCID: PMC2789489.
299. Clinical problem-solving. Anchors away. N Engl J Med. 2007 Feb 01; 356(5):504-9.Calfee CS, Shah SJ, Wolters PJ, Saint S, King TE. PMID: 17267911.
300. The influence of perceived control of asthma on health outcomes. Chest. 2006 Nov; 130(5):1312-8.Calfee CS, Katz PP, Yelin EH, Iribarren C, Eisner MD. PMID: 17099005.
301. Therapeutic value of a lung protective ventilation strategy in acute lung injury. Chest. 2005 Nov; 128(5):3089-91.Matthay MA, Calfee CS. PMID: 16304246.
302. Recent advances in mechanical ventilation. Am J Med. 2005 Jun; 118(6):584-91.Calfee CS, Matthay MA. PMID: 15922687.